Combination - Brigatinib (Alunbrig™) & Bevacizumab (Avastin™)
Last Updated: 05/1/25
	
Status: Solid Tumor and NF2 Clinical Trial
	
		
		
			
				Administered By:
			
			
				Pill - Oral, And IV
			
		 
		
			
				Tumor Target:
			
			
				Solid Tumors; Schwannoma, Meningioma, & possibly Ependymoma 
			
		 
		
			
				Inhibits:
			
			
				anaplastic lymphoma kinase (ALK) and 
epidermal growth factor receptor (EGFR) inhibitor
			
		 
 
	Brigatinib (Alunbrig™) is a clinical trial tumor drug treatment listed for solid tumors. 
	Early mouse trial studies suggest brigatinib may have good results with the reduction of size in solid tumors including; schwannoma and meningioma.
	During the mouse trials no growth was seen with long treatment breaks, followed by continued size reduction when the treatment continued 
	again later. If this holds for human trials, breaks for healing from possible side effects or for treatments of other health issues.
Treatment Availability
Results in the Mouse Trial Phase
Side Effects
Source Information
	
		
			 "Clinical Trials" () 
https://clinicaltrials.gov//
			 "Google Scholar" () 
https://scholar.google.com/