Home > Treatment Options > Tumor Suppressors > Clinical Trials >

Lapatinib (Tykerb™)

Last Updated: 01/29/20

Status: Currently a NF2 Clinical Trial

Chemical Structure, Lapatinib

Trade Name:
Tykerb, Lapatinib Ditosylate, GW572016, 231277-92-2,
GW 572016, Tycerb, 1xkk, Lapatinib (INN), Lapatinib [INN]
Pharmaceutical Company:
Legal Status:
℞ - Prescription Only
Administered By:
Pill - Oral
Tumor Target:
Vestibular Schwannoma
Protein Target:
TKI and EGFR Inhibitors
NF2 Trials:
NCT01207687 &
Unknown: NCT00863122


Lapatinib causes fatigue for several hours, medication should be taken at nighttime before sleep, not in the morning.

Other Known Uses

Breast cancer and tumors developed Solid Tumor.

Side Effects

Minimal Side Effects

Major side effects are uncommon. Since people with NF2 are taking these medications at a low dose, only minimal side effects are common. However, long term use is primarily where these major side effects take place. Monthly Blood and Urine Tests can usually point to an issue before it's a real problem. Talk to your doctor.

  • Memory Loss
  • Acne
  • Nail Infections
  • Vision - Light Sensitivity

Additional Side Effects to Watch for:

  • Liver Damage
  • Anemia
  • Low White Cell Count
  • Low Platlet Count
  • Risk of Infection
  • Nausea
  • Vomiting
  • Diarrhea
  • Belly Pain
  • Skin Irritation
  • Rash
  • Mouth Irritation
  • Numbness / Tingling of Hands and Feet
  • Fatigue
  • Irregular Menstrual Cycle

4. Warning:

Liver Damage: Look for dark urine, feeling tired, not hungry, nausea, vomiting or yellowing of skin and/or eyes.

What is NF2? | About Us | Treatment Options | Sitemap

Site Search

Disclaimer: Neurofibromatosis Type 2 - Information and Services, www.nf2is.org, is not run by medical experts, affiliated with any healthcare organization or any other company. No assurance can be made to the accuracy or completeness of the information provided here, the accuracy of other sites to which this site links, or of sites that link to this site. - Read More

Copyright © 2021