Ohio State University Tumor Suppressors

In a Medical Journal Report listed in PubMed, on July 21, 2011, "AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas", it discussed how none of the tumor suppressors to date have been approved by the FDA, so additional considerations need to be looked into.

Having obtained study funding from Advocure NF2 to do research for AR-42 and a list of possible Natural treatments, results conclusions to date show AR42 as a favorable treatment as well as six of the twenty three naturals already reviewed.

AR-42

For NF2, a tumor suppressor treatment should inhibit both VS and meningiomas. AR42 is a AR42, a novel histone deacetylase inhibitor.

In the study at Ohio State University, mice trials done indicated that, the potent inhibitor activity of AR42 in Schwannoma and Meningioma cells suggests that AR42 should be further evaluated as a potential treatment for NF2-associated tumors.

Read more about AR42

Naturals

Potential Naturals Schwannoma and Meningioma Inhibitors:

• Silvestrol
• Episilvestrol
• Bruceantin
• 13-Acetoxyrolandrolide
• Cucurbitacin D
• A2183D2F4K2

Complete Naturals Study List included:

• Silvestrol
• Episilvestrol
• Bruceantin
• Bruceine
• 13-Acetoxyrolandrolide
• Cucurbitacin D
• Dichamanetin
• Antidesmon
• A6169D3F2-5-2A
• A5777D1F5K5
• A5753D2F3K1
• A5753D2F5K2
• A5753D2F5K3
• A5984D2F5K1
• A5984D2F5K5
• A5984D2F3K7
• A2183D2F4K1
• A2183D2F4K2
• A2183D2F3K4
• CAPE (caffeic acid phenylethyl ester, an active ingredient of Propolis)
• Curcumin
• Resveratrol
• Sulforaphane

Others to be tested further:

• Honokiol (Magnolia)
• EGCG (Green Tea)
• Bosweillia
• Quercetin

Citations

• Advocure NF2:
  OSU Study Update
• PubMed - Medical Journal Abstract:
  AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas