Individuals who are born with Ring Chromosome 22 and may also develop NF2 tumors due to the damage to the 22nd chromosome.
Chromosome Ring 22, Ring Chromosome 22, r(22), Ring 22
The development of Ring Chromosome 22, occurs when there is a break in Chromosome 22 and the genes within the chromosome form a ring, by breaking into two sections and reforming together. Brakes in Chromosome 22 can happen at different points and could determine what issues an individual might face.
If a break occurs near the NF2 gene, it is possible for an individual with Ring Chromosome 22 will also develop NF2.
The occurrence is completely random, not affecting people in any part of the world or race any more frequently than others.
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